The purpose of the present study was to investigate the hydrotrophic solid dispersions of Indomethcin(IND) with hydrotrophic agents like sodium benzoate, urea & citric acid. Solid dispersions were prepared by hydrotrophy method. The prepared solid dispersions were subjected to particle size analysis, solubility analysis,in vitro dissolution , Fourior Infra Red Spectroscopy, Differential Scanning Calorimetry etc. It was observed that dissolution rate of IND enhanced to a great extent by solid dispersion technique using sodium benzoate, Urea and citric acid as hydrotrophic agents.
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